Checking if your kit is complete...
Looks good
Note (probably harmless): No library found for -lcrypto
Writing Makefile for Crypt::OpenSSL::SMIME
cp SMIME.pm blib/lib/Crypt/OpenSSL/SMIME.pm
AutoSplitting blib/lib/Crypt/OpenSSL/SMIME.pm (blib/lib/auto/Crypt/OpenSSL/SMIME)
/home/cpanrun/ia64-lp64/build/5.8.2/bin/perl /home/cpanrun/ia64-lp64/build/5.8.2/lib/5.8.2/ExtUtils/xsubpp  -typemap /home/cpanrun/ia64-lp64/build/5.8.2/lib/5.8.2/ExtUtils/typemap -typemap perlobject.map -typemap typemap  SMIME.xs > SMIME.xsc && mv SMIME.xsc SMIME.c
Please specify prototyping behavior for SMIME.xs (see perlxs manual)
cc -c   -D_POSIX_C_SOURCE=199506L -D_REENTRANT -Ae -D_HPUX_SOURCE -Wl,+vnocompatwarnings +DD64 -DNO_HASH_SEED -D_LARGEFILE_SOURCE -D_FILE_OFFSET_BITS=64 -fast +DSitanium2 +Ofltacc=strict   -DVERSION=\"0.02\" -DXS_VERSION=\"0.02\" +Z "-I/home/cpanrun/ia64-lp64/build/5.8.2/lib/5.8.2/IA64.ARCHREV_0-thread-multi-LP64/CORE"   SMIME.c
Error 112: "SMIME.xs", line 3 # Include file <openssl/crypto.h> not found.
    #include <openssl/crypto.h>
             ^^^^^^^^^^^^^^^^^^
Error 112: "SMIME.xs", line 4 # Include file <openssl/pem.h> not found.
    #include <openssl/pem.h>
             ^^^^^^^^^^^^^^^
Error 112: "SMIME.xs", line 5 # Include file <openssl/err.h> not found.
    #include <openssl/err.h>
             ^^^^^^^^^^^^^^^
Error 112: "SMIME.xs", line 6 # Include file <openssl/pkcs12.h> not found.
    #include <openssl/pkcs12.h>
             ^^^^^^^^^^^^^^^^^^
Error 112: "SMIME.xs", line 7 # Include file <openssl/x509.h> not found.
    #include <openssl/x509.h>
             ^^^^^^^^^^^^^^^^
Error 419: "SMIME.xs", line 58 # 'X509' is used as a type, but has not been defined as a type.
        X509 *cert;
        ^^^^       
Error 419: "SMIME.xs", line 59 # 'X509' is used as a type, but has not been defined as a type.
            X509 *signer;
            ^^^^         
Error 419: "SMIME.xs", line 60 # 'BIO' is used as a type, but has not been defined as a type.
            BIO *bio_err;
            ^^^          
Error 419: "SMIME.xs", line 61 # 'EVP_CIPHER' is used as a type, but has not been defined as a type.
            EVP_CIPHER *cipher;
            ^^^^^^^^^^         
Error 419: "SMIME.xs", line 64 # 'X509_STORE' is used as a type, but has not been defined as a type.
            X509_STORE *store;
            ^^^^^^^^^^        
Error 24: "SMIME.xs", line 65 # '}' expected instead of 'EVP_PKEY'.
            EVP_PKEY *key;
            ^^^^^^^^      
Error 20: "SMIME.xs", line 66 # '{' expected before '*'.
            STACK_OF(X509) *encerts;
                           ^        
Error 699: "SMIME.xs", line 66 # Error limit reached; halting compilation.
            STACK_OF(X509) *encerts;
                           ^        
make: *** [SMIME.o] Error 2